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Leonard F Bjeldanes Selected Research

glucobrassicin

11/2012Target protein interactions of indole-3-carbinol and the highly potent derivative 1-benzyl-I3C with the C-terminal domain of human elastase uncouples cell cycle arrest from apoptotic signaling.
9/2011Indole-3-carbinol downregulation of telomerase gene expression requires the inhibition of estrogen receptor-alpha and Sp1 transcription factor interactions within the hTERT promoter and mediates the G1 cell cycle arrest of human breast cancer cells.

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Leonard F Bjeldanes Research Topics

Disease

26Breast Neoplasms (Breast Cancer)
11/2013 - 02/2002
17Neoplasms (Cancer)
07/2012 - 02/2002
4Prostatic Neoplasms (Prostate Cancer)
09/2009 - 06/2003
2Carcinogenesis
02/2008 - 04/2005
2Carcinoma (Carcinomatosis)
11/2005 - 12/2003
1Arthritis (Polyarthritis)
01/2013
1Autolysis
08/2010
1Hypoxia (Hypoxemia)
05/2008
1Virus Diseases (Viral Diseases)
05/2008
1Dehydration (Water Stress)
02/2008
1Hepatocellular Carcinoma (Hepatoma)
04/2006
1Endometrial Neoplasms (Endometrial Cancer)
02/2004

Drug/Important Bio-Agent (IBA)

21indole-3-carbinolIBA
11/2012 - 02/2002
143,3'-diindolylmethane (diindolylmethane)IBA
11/2013 - 03/2002
12indoleIBA
11/2013 - 08/2002
7Estrogens (Estrogen)FDA Link
09/2011 - 08/2002
5Estrogen Receptor alphaIBA
09/2011 - 04/2005
5Estrogen ReceptorsIBA
04/2010 - 03/2002
4Proteins (Proteins, Gene)FDA Link
11/2012 - 08/2002
4PhytochemicalsIBA
09/2011 - 04/2005
4Antineoplastic Agents (Antineoplastics)IBA
04/2010 - 12/2003
3Pancreatic Elastase (Elastase)IBA
11/2012 - 12/2008
3AndrogensIBA
09/2009 - 06/2003
3Interferon-gamma (Interferon, gamma)IBA
05/2008 - 03/2005
3DNA (Deoxyribonucleic Acid)IBA
04/2006 - 03/2002
2Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA
11/2012 - 06/2010
2glucobrassicinIBA
11/2012 - 09/2011
2TamoxifenFDA LinkGeneric
08/2010 - 03/2005
2Hormones (Hormone)IBA
04/2010 - 01/2004
2Androgen Receptors (Androgen Receptor)IBA
09/2009 - 11/2005
2Cyclin EIBA
12/2008 - 03/2005
2Androgen Antagonists (Antiandrogens)IBA
12/2003 - 06/2003
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
11/2013
1Ethanol (Ethyl Alcohol)IBA
01/2013
1Methanol (Carbinol)IBA
01/2013
1LuciferasesIBA
07/2012
1Telomerase (Telomerase Reverse Transcriptase)IBA
09/2011
1Sp1 Transcription FactorIBA
09/2011
1Biological ProductsIBA
10/2010
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
06/2010
1NF-kappa B (NF-kB)IBA
06/2010
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
04/2010
1rho-Associated KinasesIBA
05/2009
1Glucose (Dextrose)FDA LinkGeneric
05/2008
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2008
1FurinIBA
05/2008
1Reactive Oxygen Species (Oxygen Radicals)IBA
05/2008
1Immunoglobulin A (IgA)IBA
05/2008
1PhosphofructokinasesIBA
05/2008
1CytokinesIBA
05/2008
1liquiritigeninIBA
02/2008
1alkoxyl radicalIBA
02/2008
1NitrogenIBA
02/2008
1CarbonIBA
02/2008
1Cytostatic AgentsIBA
02/2008
1Cyclin-Dependent Kinases (cdk Proteins)IBA
12/2006
1Tumor Suppressor Protein p53IBA
12/2006
1Estrogen Receptor betaIBA
12/2006
1Progesterone Receptors (Progesterone Receptor)IBA
12/2006
1Adenosine Triphosphate (ATP)IBA
05/2006
1AcidsIBA
04/2005
1CyclinsIBA
03/2005
1Phosphotransferases (Kinase)IBA
03/2005
1Cyclin-Dependent Kinase 2IBA
03/2005
1Interferon gamma ReceptorIBA
07/2004
1InterferonsIBA
07/2004
1LigandsIBA
02/2004
1IndolesIBA
01/2004
1Prostate-Specific Antigen (Semenogelase)IBA
12/2003
1ThymidineIBA
12/2003
1Propidium (Propidium Iodide)IBA
12/2003
1Flutamide (Eulexin)FDA LinkGeneric
12/2003
1Transcription Factors (Transcription Factor)IBA
01/2003
1Cyclin-Dependent Kinase 6IBA
01/2003
1Messenger RNA (mRNA)IBA
08/2002

Therapy/Procedure

2Therapeutics
12/2008 - 02/2008
1Drug Therapy (Chemotherapy)
06/2010